I run MythTV and use a serial IR transceiver (made by IguanaWorks) to read my remote control and blast to a ShawDirect satellite set top box.
I am finding that the linux kernel used in F14 188.8.131.52-96.fc14 sometimes does not load the lirc_serial module correctly, complaining that it is already in use when its not even loaded.
I found a somewhat stable set of steps to load the lirc_serial module.
The other thing I fund is that if I run these commands from within a bash script the lirc modules STILL might not load.
I run them on manually on the commandline.